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    钙结合蛋白Calponin (Basic)抗体

    产品型号:
    产品产地: 中国大陆
    访问次数: 1495
    发布时间: 2016/3/29 15:37:15
    Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
    thought to be involved in the regulation of smooth muscle contraction.
  钙结合蛋白Calponin (Basic)抗体
Clone 26A11
7 mL BOND ready-to-use PA0416 P (HIER)
Antigen Background
Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
thought to be involved in the regulation of smooth muscle contraction. The
expression of basic calponin is reported to be restricted to smooth muscle
cells and is a marker of the differentiated contractile phenotype of developing
smooth muscle. Vascular smooth muscle cells convert to a synthetic
dedifferentiated phenotype when this protein is lost and this is a key stage in
both atherosclerosis and restenosis of coronary arteries after balloon
angioplasty. It is thought that basic calponin exerts its effect via the cortical
actin cytoskeleton and therefore influences proliferation, the transformed
phenotype and the metastatic potential of tumor cells. Basic calponin mRNA
is expressed in smooth muscle of prostate, bowel and aorta whereas neutral
and acidic calponin mRNAs are expressed in non-smooth muscle tissues
such as heart, placenta, lung, kidney, pancreas, spleen, testis and ovary as
well as in smooth muscle-containing tissues.


Breast carcinoma: immunohistochemical staining with BOND ready-to-use Calponin (Basic)
(26A11) using BOND Polymer Refine Detection.

更新时间:2023/11/10 8:29:10


标签:钙结合蛋白抗体   Calponin   Clone   26A11   

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