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产品名称: |
徕卡抗体Anaplastic Lymphoma Kinase |
产品型号: |
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产品产地: |
中国大陆 |
访问次数: |
1651 |
发布时间: |
2016/3/28 15:13:38 |
Anaplastic large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and the epithelial membrane antigen (EMA). |
徕卡抗体Anaplastic Lymphoma Kinase Clone 5A4 7 mL BOND ready-to-use PA0306 P (HIER) Antigen Background Anaplastic large cell lymphoma (ALCL) is usually composed of large pleomorphic cells which are reported to express CD30 antigen and the epithelial membrane antigen (EMA). These tumor cells tend to occur in younger individuals and may be associated with cutaneous and extranodal involvement. A proportion of these cases contain a chromosomal translocation t(2;5) (p23; q35). This results in a hybrid gene encoding part of the nucleophosmin (NPM) gene joined to the cytoplasmic domain of the anaplastic lymphoma kinase (ALK) gene, giving rise to the protein, p80. Large cell lymphomas account for approximately 25 percent of all non-Hodgkin's lymphomas in children and young adults, of which one third carries the NPMALK gene translocation.
Human anaplastic lymphoma: immunohistochemical staining for anaplastic lymphoma kinase (p80) using NCL-ALK. Note cytoplasmic staining of large pleomorphic cells. Paraffin section.
更新时间:2024/4/3 14:23:06 标签: ALCL 克隆抗体 Anaplastic Lymphoma Kinase
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